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    Blog

    Blog: clinical trials and diagnostics notes

    Two kinds of post in one place: the clinical trials and validation studies behind the assays, and practical notes for distributors, clinics, laboratories and farms. New posts are added as the catalogue grows.

    Clinical trials

    Published studies, field validations and case reports on the assays: produced by the manufacturers' academic partners, hosted here so a customer can read the data rather than take our word for it. All clinical trials →

    Comparative performance vs. a reference method

    Dirofilaria immitis / D. repens

    Point-of-care isothermal detection compared against an established heartworm test.

    PDF · 1 page →

    Clinical case report

    Heartworm

    A dog misdiagnosed with heartworm by a lateral-flow rapid test, resolved by molecular testing.

    PDF · 2 pages →

    Point-of-care validation study

    Feline & canine parvovirus (FPV / CPV)

    Isothermal loop-mediated amplification evaluated for chairside parvovirus detection.

    PDF · 10 pages →

    Field validation

    Ehrlichia

    Independent field validation carried out in Thailand.

    PDF · 10 pages →

    Peer-reviewed publication, 2025

    Molecular point-of-care testing

    Received October 2025, revised November 2025, with named academic editors.

    PDF · 16 pages →

    Point-of-care validation study

    Feline calicivirus (FCV)

    Isothermal loop-mediated amplification evaluated for chairside FCV detection.

    PDF · 8 pages →

    Point-of-care validation study

    Feline & canine coronavirus (FCoV / CCoV)

    Isothermal loop-mediated amplification evaluated for chairside coronavirus detection.

    PDF · 8 pages →

    Articles

    Practical posts: what a disease looks like, what to sample, which method finds it and how to read the result. Each links to the products it discusses.

    A reference chart circulated among shrimp farmers: 28 signs of disease in whiteleg shrimp, each with an arrowAquaculture PCR · 2026-10-13

    Disease signs in whiteleg shrimp: 28 things a farmer sees, and the PCR that names the cause

    28 field signs of disease in whiteleg shrimp (L. vannamei), from white spots and red tail to white faeces, and which PCR test confirms the cause of each.

    A single-channel isothermal dock on the consulting table. The sealed card amplifies nucleic acid at one constaIsothermal amplification · 2026-09-22

    Isothermal amplification vs lateral-flow vs laboratory PCR: choosing the right test for infectious disease in dogs and cats

    Lateral-flow, chairside isothermal amplification and laboratory PCR compared for dogs and cats: what each detects, sensitivity, turnaround, multiplexing and cost.

    A benchtop immunofluorescence reader in a clinic laboratory. The cassette is read by fluorescence and the resuImmunofluorescence · 2026-09-22

    Quantitative immunofluorescence vs rapid tests for CRP and SAA: why a number changes case management

    Canine CRP and feline SAA compared across lateral-flow, quantitative immunofluorescence and chemiluminescence: reference ranges, kinetics and when a number decides the case.

    A lyophilised qPCR kit for aquaculture pathogens. The reagent is dried in the tube and rehydrated with the samAquaculture PCR · 2026-09-22

    Lyophilised qPCR vs wet-reagent PCR and LAMP for shrimp pathogen screening on the farm

    Nested PCR, wet-reagent qPCR, LAMP and freeze-dried qPCR compared for shrimp pathogen screening, with WOAH sampling numbers and the farm workflow.

    Real-time PCR analysers in a veterinary laboratory. Each fluorescence channel carries one target; a four-channReal-time PCR · 2026-09-22

    Multiplex real-time PCR panels vs single-target tests: syndromic testing in the veterinary laboratory

    Multiplex real-time PCR panels versus single-target kits: how multiplexing works, what it costs in sensitivity and validation, and when singleplex is still right.

    Hepatopancreas (boxed) in four post-larvae. Colour and fullness of the organ vary with feed, moult stage and hAquaculture PCR · 2026-09-21

    EHP in shrimp: why the hepatopancreas looks normal until it is too late

    Enterocytozoon hepatopenaei (EHP) causes slow growth and size variation in farmed shrimp. What the hepatopancreas shows, how spores spread, and how farms screen by qPCR.

    White calcified spots on the carapace and a reddish body are the classic signs, but by the time they appear thAquaculture PCR · 2026-09-21

    White spot syndrome virus: three to ten days from first sign to empty pond

    White spot syndrome virus (WSSV) can empty a shrimp pond within a week. What the white spots are, how the virus enters a farm, and which PCR screening points keep it out.

    A single-channel dock on the consulting table. The card is sealed after the sample is added, so there is no reIsothermal amplification · 2026-09-21

    Chairside molecular testing: what changes when PCR-grade results arrive in 30 minutes

    Isothermal amplification puts a nucleic-acid test on the consulting table: one swab, up to six pathogens, result in about 30 minutes. When it replaces a send-out PCR, when it does not, and how clinics use it.

    A combination cassette with separate control (C) and test (T) lines for each analyte. The control line must apRapid test · 2026-09-21

    How to read a veterinary rapid test correctly, and when not to trust it

    Control line, timing window, faint lines, invalid results, storage and vaccine interference: the rules for reading a lateral-flow veterinary rapid test, for clinics, shelters and distributors training their customers.